Vascular pathologic changes in the flexor tenosynovium (subsynovial connective tissue) in idiopathic carpal tunnel syndrome

Carpal tunnel syndrome pathophysiology: role of subsynovial connective tissue.

Carpal tunnel syndrome (CTS) is a very common pathology. Its most common diagnosis is idiopathic. Although it is accepted that chronic increase in pressure within the carpal tunnel is responsible for median nerve neuropathy, the exact pathophysiology leading to this pressure increase remains unknown. All the histological studies of the carpal tunnel in the CTS find a noninflammatory thickening ...

Inflammation and fibrosis of transverse carpal ligament and flexor tenosynovium in severe idiopathic carpal tunnel syndrome

Background: We approached a histopathologic study of idiopathic carpal tunnel syndrome (CTS) to identify its probable causative factors. The purpose of this study was to assess the prevalence of inflammation and fibrosis in the transverse carpal ligament (TCL) and flexor tenosynovium (FT) in severe idiopathic carpal tunnel syndrome. Methods: Thirty nine patients with severe idiopathic CTS under...

MMP-2, MMP-9 and MMP-12 expression in flexor tenosynovium in idiopathic carpal tunnel syndrome

Tenascin-C and proleferative arteriosclerosis in flexor tenosynovium of idiopathic carpal tunnel syndrome

Tenascin-C and proleferative arteriosclerosis in flexor tenosynovium of idiopathic carpal tunnel syndrome Masaya Tsujii1, Hitoshi Hirata2, Masahiro Hasegawa1, Koji Akeda1, Kyoko Imanaka-Yoshida3, Toshimichi Yoshida3, Atsumasa Uchida1 1Orthopaedic Surgery, Mie University, Tsu, Japan; 2Hand Surgery, Nagoya University, Nagoya, Japan; 3Pathology, Mie University, Tsu, Japan [email protected]...

Involvement of Matrix Metalloproteinase-2 for the Proloferative Arteriosclerosis in the Flexor Tenosynovium of Idiopathic Carpal Tunnel Syndrome

THE FLEXOR TENOSYNOVIUM OF IDIOPATHIC CARPAL TUNNEL SYNDROME *Tsujii, M, +*Hirata, H, *Iida ,R, *Sugimoto, N, ** Morita, A, * Yoshida, T, *Kyoko, I-Y, **Fujisawa, K, *Uchida, A. +* Mie University, Faculty of Medicine, **Suzuka Kaisei Genral Hospital email address; [email protected] Introduction Idiopathic carpal tunnel syndrome (CTS) is estimated to occur in 1 % of the general popul...